400-800 mcg foliumzuur per dag verlaagt een beroerte

Research Question:
There is an ongoing conflict about preventing a stroke by foliumsupplementen. It was therefore carried out this review article. 

Swallowing folic acid supplements lowers the chances of getting a stroke?

Study Design:
This overview article contained 15 Rcts with 55764 participants.

Results and conclusions:
The ondezoekers found that swallowing folic acid supplements (n = 55764) the chance of getting a stroke significantly with 8% [RR = 0.92, 95% CI = 0.86-1.00, p = 0.038] reduced.

The ondezoekers took place in 10 Rcts with partial or no folic acid fortification, that swallowing folic acid supplements (n = 43426) the chance of getting a stroke significantly with 11% [RR = 0.89, 95% CI = 0.82-0.97, p = 0.010] reduced. The reduced risk in these 10 studies increased to 23% among the population with a low percentage of 89%) statinegebruik (.

The ondezoekers took place in 5 Rcts with folic acid fortification, that swallowing folic acid supplements (n = 12338) the chance of getting a stroke not significantly with 3% [RR = 1.03, 95% CI = 0.88-1.21, p = 0.69] increased.

The ondezoekers concluded that swallowing folic acid supplements (400-800 micrograms per day) the chance of getting a stroke in the population without or with reduced partial folic acid fortification. The reduced risk rose as less Statin was used.

Original title:
Efficacy of folic acid supplementation in stroke prevention: new insight from a meta-analysis by Huo Y, Qin X, [...], Wang X.

Link:  
http://www.ncbi.nlm.nih.gov/pubmed/22607506

Additional information about El Mondo:
It is not obligatory in Netherlands wetttelijk to add folic acid to foods, also called folic acid fortification called. The only "obligation" is to add vitamins A and D to margarine and low-fat margarine and iodine to bread and pastry products.

It is not possible through feeding daily 400 micrograms (mcg) folic acid to get inside.
Find here more studies on foliuzuur.