Een kransslagader calcium score boven 10 verhoogt hart- en vaatziekten onder patiënten met suikerziekte type 2

Research Question:
Is there a link between a high coronary artery calcium score and getting heart disease in people with type 2 diabetes?

Study Design:
This overview article contained 8 prospective cohort studies with 6521 participants with diabetes type 2, 802 people with heart disease and a mean follow-up duration of 5.18 years.

Results and conclusions:
The researchers found that in people with type 2 diabetes, a coronary artery calcium score above 10 compared to under 10, the risk of both getting heart disease events significantly with 447% as all-cause mortality [RR = 5.47, 95% CI = 2.59-11.53, I2 = 82.4%, p 0.001] increased.
The sensitivity was 94% [95% BI = 89%-96%] and the specificity was 34%[95% BI = 24%-44%].

The researchers concluded that people with type 2 diabetes that a coronary artery calcium score above 10, had had an increased chance of getting both heart disease and all-cause mortality. The sensitivity of the coronary calcium score was high and the specificity was low.

Original title:
Coronary artery calcium score prediction of all cause mortality and cardiovascular events in people with type 2 diabetes: systematic review and meta-analysis by Kramer CK, Zinman B, [...], Retnakaran R.

Link:
http://www.bmj.com/content/346/bmj.f1654.abstract

Additional information about El Mondo:
The calcium score is an investigation into the levels of calcium in the coronary arteries with a CT scan. Calcium in the coronary arteries of the assassin the artery disease, which is the main cause of heart disease.

Read more about calcium.