Een verlaagd risico op mortaliteit tot 40 g alcohol per dag maar een verhoogd risico boven 40 g onder mannen

Research Question:
What is the link between drinking alcohol and mortality risk in time look like?

Study Design:
This overview article contained 9 cohort studies between 1991-2010 with 10490 62950 participants and people who were died during the studies.

There was a moderate between-study heterogeneity but no evidence of publication bias. Studies among women were very scarce and therefore could there is no meta-analysis carried out.

Results and conclusions:
The researchers found for men in a random-effect model a reduced risk of mortality (death to) at a consumption of up to 40 g of alcohol per day but an increased risk of above 40 g of alcohol per day.

The researchers found reduced risk of a significant for men, 10% [pooled RR = 0.90, 95% CI = 0.81-0.99] on mortality for 1-29 grams of alcohol per day.

The researchers found, a non-significant increased risk for men of 19% [pooled RR = 1.19, 95% CI = 0.89-1.58] on mortality for 30-59 grams of alcohol per day.

The researchers found for men, a non-significant increased risk of 52% [pooled RR = 1.52, 95% CI = 0.78-2.98] on mortality for 60 grams of alcohol or more a day.

The researchers concluded that there is a curvilinear relationship existed between drinking alcohol in the time and the chance of mortality in men.

Original title:
Alcohol consumption over time and risk of death: a systematic review and meta-analysis by Jayasekara H, English DR, [...], Macinnis RJ.


Additional information about El Mondo:
Find here more studies on alcohol consumption.