Objectives:
Which disease-modifying osteoarthritis drugs improve knee and hip osteoarthritis among adults?

Study design:
This review article included 28 randomized controlled trials (RCTs) with 11,890 patients.

Objectives:
There is much debate regarding the source/quality of dietary proteins in supporting indices of skeletal muscle anabolism. Therefore, this review article has been conducted.

Objectives:
What are the efficacy and safety of COVID-19 vaccines and the differences between vaccine types?

Study design:
This review article included 8 RCTs with a total of 158,204 subjects.

The 8 RCTs provided data on 2 mRNA vaccines (mRNA-1273 and BNT162b2), 2 virus-vectored vaccines (ChAdOx1-S and Gam-COVID-Vac) and 3 inactivated vaccines (CoronaVac, HB02 and WIV04).

Objectives:
Despite growing evidence that type 2 diabetes is associated with dementia, the question of whether intensive glucose control can prevent or arrest cognitive decline remains unanswered. Therefore, this review articles (meta-analysis) has been conducted.

Objectives:
Does grapes/grape products supplementation improve glycemic indices (like HOMA-IR, Hb1Ac and fasting insulin level) in adults or in other words, does eating grapes or grape products causally improve glycemic indices in adults?

Study design:
This review article included 29 RCTs with a total of 1,297 participants.

Results and conclusions:

Objectives:
Systematic reviews of case-control studies evaluating the relationship between dietary salt intake and gastric cancer showed a positive association, however a quantitative analysis of longitudinal cohort studies is lacking. Therefore, this review article has been conducted.

Does a high salt intake increase gastric cancer risk?

Study design:
This review article contained 10 cohort studies with 268,718 participants, of which 1,474 gastric cancer events and a follow-up of 6-15 years.

Objectives:
To overcome the limitations of conventional malaria rapid diagnostic tests (cRDTs) in diagnosing malaria in patients with low parasitaemia, ultrasensitive malaria rapid diagnostic tests (uRDTs) have recently been developed, with promising results under laboratory conditions. Therefore, this review article has been conducted.

Objectives:
The influence of dietary fat upon breast cancer mortality remains largely understudied despite extensive investigation into its influence upon breast cancer risk. Therefore, this review article has been conducted.

Does higher total fat or saturated fat dietary intake increase risk of breast-cancer-specific death (breast cancer mortality) among women?

Study design:
This review article included 15 prospective cohort studies investigating total fat and/or saturated fat intake (g/day) and breast cancer mortality.

Objectives:
Clinical trials assessing the efficacy of IL-6 antagonists in patients hospitalized for COVID-19 have variously reported benefit, no effect and harm. Therefore, this review article has been conducted.

Does administration of IL-6 antagonists reduce 28-day all-cause mortality among patients hospitalized for COVID-19?

Study design:
This review article included 27 RCTs with a total of 10,930 patients (median age, 61 years (52-68 years) and 3,560 (33%) were women).

Objectives:
Even though many studies have examined the possible effect of low-fat diet on breast cancer survival, the relationship remains unclear. Therefore, this review article has been conducted.

Does low-fat diet reduce risk of recurrence of breast cancer?

Study design:
This review article included 2 randomized controlled trials (RCTs) and 1 large multi-center prospective cohort study with 9,966 breast cancer patients.