Foliumzuursupplementen verlagen het homocysteïnegehalte bij mensen met suikerziekte type 2

Research Question:
The evidence for the effects of folic acid on plasma homocysteine levels and the total the glycemic control in people with type 2 diabetes are contradictory. It was therefore carried out this review article.

The total plasma homocysteine levels and folic acid supplements improve the glycemic control in people with type 2 diabetes?

Study Design:
This overview article contained 4 studies with 183 patients with diabetes type 2.

Results and conclusions:
The meta-analysis showed that folic acid supplements had a significant effect on the total plasma homocysteine levels in patients with type 2 diabetes. The weighted mean difference was-3.52 [95% CI =-4.44 to-2.60]. Significant is, there is a link at 95% reliability.

The meta-analysis showed that folic acid supplements had a non-significant effect on the HbA1c levels in patients with type 2 diabetes. The weighted mean difference was-0.37 [95% CI =-1.10 to 0.35]. Non-significant is, there is no link.

The researchers concluded that folic acid supplements the total plasma homocysteine levels in patients with type 2 diabetes reduced and there was a trend to recognize in improving glycemic control.

Original title:
Effect of folic acid supplementation on plasma total homocysteine levels and glycemic control in patients with type 2 diabetes: A systematic review and meta-analysis by Sudchada P, Saokaewemail S, [...], Khaithong W.

Link:
http://www.sciencedirect.com/science/article/pii/S016882271200215X

Additional information about El Mondo:
Read more about folic acid and homocysteine levels in the presentation the high folic acid.