Foliumzuursupplementen verlagen mogelijk een beroerte

Research Question:
Swallowing folic acid supplements will lower the chance of getting heart disease?

Study Design:
This overview article contained 26 Rcts with 58804 participants.

Results and conclusions:
The researchers found that taking folic acid supplements the chance of getting cardiovascular diseases (CVD) are not significantly with 2% [95% CI = 0.95-1.02, p = 0.36] reduced. Not significant is, there is no link to a 95% reliability.

The researchers found that taking folic acid supplements the chances of getting coronary heart disease (CHD) is not significantly with 3% [95% CI = 0.98-1.08, p = 0.23] increased.

The researchers found that swallowing folic acid supplements the risk of all-cause mortality (death to all causes) not significant with 0% [95% CI = 0.96, p = 0.92-1.04] increased.

The researchers found that taking folic acid supplements the chance of getting a stroke not significant with 7% [95% CI = 0.86-1.00, p = 0.05] reduced.

The researchers concluded that taking folic acid supplements the chance of getting a stroke may be reduced. Possible because the found p-value for getting a stroke was equal to 0.05.

Original title:
Efficacy of folic acid supplementation in cardiovascular disease prevention: an updated meta-analysis of randomized controlled trials by Yang HT, Lee M, [...], Saver JL.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/22884409

Additional information about El Mondo:
Find out more about studies with folic acid.