Groenten en fruit verlagen blaaskanker

Research Question:
Observational studies suggest a link between the vegetable and fruit consumption and the risk of getting bladder cancer, however the results are controversial. It was therefore carried out this review article.

Eating fruits and vegetables lowers the chances of getting bladder cancer?

Study Design:
This overview article contained 31 observational studies with 1121649 participants, of which 12610 people with bladder cancer.
Subgroup analyses showed that the study design and the sex are possible sources of heterogeneity.
There was some evidence of publication bias for fruit, citrus fruits and yellow-orange vegetables.

Results and conclusions:
The researchers found that eating lots of fruits and vegetables, the chances of getting bladder cancer significantly with 17% [RR = 0.83, 95% CI = 0.69-0.99] reduced.

The researchers found that eating a lot of fruit, the chances of getting bladder cancer significantly with 23% [RR = 0.77, 95% CI = 0.69-0.87] reduced.

The researchers found that eating lots of vegetables, the chances of getting bladder cancer significantly with 19% [RR = 0.81, 95% CI = 0.70-0.93] reduced.

The researchers found that eating lots of cruciferous vegetables, the chances of getting bladder cancer significantly with 16% [RR = 0.84, 95% CI = 0.77-0.91] reduced.

The researchers found that eating a lot of citrus fruits, the chances of getting bladder cancer significantly with 21% [RR = 0.79, 95% CI = 0.68-0.91] reduced.

The researchers found that eating a lot of yellow-orange vegetables, the chances of getting bladder cancer significantly with 26% [RR = 0.74, 95% CI = 0.66-0.84] reduced.

The researchers found that eating 30 grams of citrus fruit per day, the chances of getting bladder cancer significantly with 13% [RR = 0.87, 95% CI = 0.78-0.96] reduced.

The researchers found that eating 60 grams of citrus fruit per day, the chances of getting bladder cancer significantly with 20% [RR = 0.80, 95% CI = 0.67-0.94] reduced.

The researchers found that eating citrus fruits 90 grams per day, the chances of getting bladder cancer significantly with 21% [RR = 0.79, 95% CI = 0.66-0.94] reduced.

The researchers found that eating 120 grams of citrus fruit per day, the chances of getting bladder cancer significantly with 21% [RR = 0.79, 95% CI = 0.65-0.96] reduced.

The researchers found that eating 150 grams of citrus fruit per day, the chances of getting bladder cancer significantly with 21% [RR = 0.79, 95% CI = 0.64-0.99] reduced.

The researchers found a non-linear relationship between eating yellow-orange vegetables with the reduced risk of getting bladder cancer [p for non-linearity = 0.033].

The researchers concluded that eating lots of vegetables (especially cruciferous and yellow-orange vegetables) and fruit (especially citrus fruits 30-150 grams per day) reduced the chances of getting bladder cancer.

Original title:
Intake of fruit and vegetables and risk of bladder cancer: a dose-response meta-analysis of observational studies by Yao B, Yan Y, [...], Zhao Y.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/25248495

Additional information about El Mondo:
Find here more studies on fruit and vegetables consumption.