Voedingsadvies El MondoResearch Question:
Is there a relationship between eating macronutrients and getting Parkinson's?
Study Design:
This overview article contained 32 items with 677550 participants, of which 9994 people with Parkinson's disease.
Results and conclusions:
The researchers found (in 7 articles with 1570 people with Parkinson's disease under 357827 participants) that eating a lot of protein compared to little, the chance of getting Parkinson's disease non-significant 13% [RR = 1.13, 95% CI = 0.88-1.44] increased. Non-significant is, there is no link to a 95% reliability.
The researchers found (in 8 articles with 1482 people with Parkinson's disease under 232869 participants) that eating lots of carbohydrates compared to little, the chance of getting Parkinson's disease significantly with 24% [RR = 1.24, 95% CI = 1.05-1.48] increased.
The researchers found (in 12 articles with 2936 people with Parkinson's disease under 374124 participants) that eating a lot of fat compared to little, the chance of getting Parkinson's disease non-significant 12% [RR = 0.88, 95% CI = 0.74-1.06] reduced.
The researchers found (in 6 articles with 1713 people with Parkinson's disease under 170058 participants) that eating a lot of cholesterol compared to little, the chance of getting Parkinson's disease 3% non-significant [RR = 0.97, 95% CI = 0.75-1.26] reduced.
The researchers found (in 8 articles with 1553 people with Parkinson's disease under 170317 participants) that eating a lot of calories compared to little, the chance of getting Parkinson's disease significantly with 39% [RR = 1.39, 95% CI = 1.01-1.92] increased.
The researchers found in prospective studies involving was corrected for smoking and coffee/Caffeine consumption, no significant association between getting Parkinson's disease and eating a lot:
proteins [RR = 1.02, 95% CI = 0.80-1.30].
carbohydrates [RR = 1.11, 95% CI = 0.86-1.43]
fat [RR = 0.90, 95% CI = 0.70-1.16].
cholesterol [RR = 0.89, 95% CI = 0.74-1.09].
calories [RR = 0.97, 95% CI = 0.93-1.02].
The researchers found in prospective studies involving was corrected for smoking and coffee/Caffeine consumption, that eating a lot of polyunsaturated fatty acids the chances of getting Parkinson's disease significantly with 22% [RR = 0.78, 95% CI = 0.64-0.96] reduced. Significant is, there is a link at a 95% reliability.
On the basis of the found results the researchers concluded that there is no link between eating a lot of protein, carbohydrates, cholesterol or calories and the chance of getting Parkinson's disease. But eating a lot of polyunsaturated fatty acids lowers though getting Parkinson's disease.
Original title:
Macronutrients intake and risk of Parkinson's disease: A meta-analysis by Wang A, Lin Y, [...], Zhang D.
Link:
http://www.ncbi.nlm.nih.gov/pubmed/25163395
Additional information about El Mondo:
Find here more studies on polyunsaturated fatty acids (Pufas).