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Research Question:
Eating cruciferous vegetables lowers the chances of getting lung cancer?

Study Design:
This overview article contained 30 studies. 6 cohort and case-control studies with 12 8227 people with lung cancer, examined the relationship between Lung cancer and the total amount of cruciferous vegetables while 1 cohort and case-control studies 11 the relationship between Lung cancer and examined specific cruciferous vegetables.

Results and conclusions:
The researchers found in case-control studies that eating many cruciferous vegetables (as a whole) compared to little, the chances of getting lung cancer significantly with 22% [95% CI = 0.70-0.88, no heterogeneity between the studies] reduced. Significant is, there is a link at a 95% reliability.

The researchers found in cohort studies that eating many cruciferous vegetables (minimum 8 times a month) compared to little (up to 9 times a month), the chances of getting lung cancer non-significant 17% [95% CI = 0.62-1.08, there was heterogeneity between the studies] reduced. Non-significant is, there is no link to a 95% reliability.

The researchers found that people with GSTM1 and GSTT1-nulgenotypen who ate a lot of cruciferous vegetables, ran significantly 59% [95% CI = 0.26-0.65, p for interaction was 0.01] less chances of getting lung cancer.

The researchers found in case-control studies that eating lots of broccoli compared with little, the chances of getting lung cancer significantly with 47% [95% CI = 0.34-0.83, there was no heterogeneity between the studies] reduced.

The researchers found in case-control studies that eating a lot of carbon compared to little, the chances of getting lung cancer significantly with 30% [95% CI = 0.54-0.91, there was heterogeneity between the studies] reduced.

The researchers found in 8 case-control studies that each increase of 1 serving of cruciferous vegetables (about 75 grams) the chances of getting lung cancer significantly with 26% [95% CI = 0.73-0.75] reduced.

The researchers concluded that eating many cruciferous vegetables, especially broccoli the chances of getting lung cancer, particularly in people with GSTM1 and GSTT1-nulgenotypen reduced.

Original title:
Cruciferous Vegetable Consumption and Lung Cancer Risk: A Systematic Review by Lam TK, Gallicchio L, [...], Alberg AJ.

Link:
http://cebp.aacrjournals.org/content/18/1/184.full.pdf+html

Additional information about El Mondo:
The benefits of cruciferous vegetables, such as broccoli, cabbage and Brussels sprouts is attributed to different isothiocyanate.