100 mg soja-isoflavonensupplementen per dag verlaagt het lichaamsgewicht bij niet-Aziatische postmenopauzale vrouwen

Research Question:
Swallowing of soy isoflavones lowers the blood glucose and lichaamgewicht, the sober sober insulin levels?

Study Design:
This overview article contained 9 Rcts with 528 participants for weight, 11 Rcts with 1182 participants for sober blood glucose levels and 11 Rcts with 1142 participants for sober insulin levels.

Results and conclusions:
The researchers found that postmenopausal women in non-Asian swallowing soy-isoflavonensupplementen body weight significantly with 0.515 kg [95% CI = 0.134, p = 0.008 0,895-to-] did decrease. Significant is, there is a link at a 95% reliability.

The researchers found in non-Asian postmenopausal women that swallowing of soy isoflavonensupplementen the empty blood sugar significantly [weighted average difference =-0.189, 95% CI =-.344 to-0.033] did decrease. Significant is, there is a link at a 95% reliability.

The researchers found in non-Asian postmenopausal women that swallowing of soy isoflavonensupplementen the sober insulin levels significantly [weighted average difference =-0.940, 95% CI =-1,721 to-0.159] did decrease. Significant is, there is a link at a 95% reliability.

The researchers found in subgroup analysis (to get additional information) that swallowing of soy-isoflavonensupplementen shorter than 6 months, the body weight significantly with 0.506 kg [95% CI =-0.009, p = 0.888 to-0.124] did decrease.

The researchers found in subgroup analysis (to get additional information) that swallowing of soy isoflavonensupplementen longer than 6 months, the fasting blood sugar significantly [weighted average difference =-0.270, 95% CI =-0.430 to 0.110, p = 0.001-] did decrease.

The researchers found in subgroup analysis (to get additional information) that swallowing to 100 mg soy-isoflavonensupplementen per day, reduced body weight the most.

The researchers found in subgroup analysis (to get additional information) that swallowing of soy-isoflavonensupplementen, body weight and sober insulin levels in women with a BMI smaller than 30 reduced more effectively than with a BMI greater than 30.

The researchers concluded that swallowing of soy isoflavonensupplementen the body weight, the blood glucose and insulin levels in sober sober non-Asian postmenopausal women reduced.

Original title:
Soy isoflavone supplementation could reduce body weight and improve glucose metabolism in non-Asian postmenopausal women--a meta-analysis by Zhang YB, Chen WH [...], after XL.

Link:
http://www.ncbi.nlm.nih.gov/pubmed/22858192

Additional information about El Mondo:
Type 2 diabetics often have a high body weight (BMI greater than 25 usually), a high fasting blood sugar and insulin levels sober. The main cause of type 2 diabetes is overweight and type 2 diabetes is the most important consequences of cardiovascular disease and kidney problems.

The 3 main isoflavones in soybean are genistein daidzein, and glycitein. These 3 forms are the active forms in the human body. Genistein is the most active of the three.

Products

Total isoflavones (mg)

Daidzein (mg)

Genistein (mg)

Soy beans (100 g)

128.34

46.46

73.76

Natto (100 grams)

58.93

21.85

29.04

Fried tofu (100 grams)

48.35

17.83

28

Tempeh (100 grams)

43.52

17.59

24.85

Soft tofu (100 grams)

29.24

8.59

20.6

Scientific studies show that the minimum amount of isoflavones needed to possitieve effects in the body to around 30 to 50 mg per day.