Voedingsadvies El MondoResearch Question:
Lowers eating carotenoids the chance of getting head and neck cancer?
Study Design:
This overview article contain 14 case-control studies and 1 prospective cohort studies.
Results and conclusions:
The researchers found that the ingest of many beta-carotene equivalents through feeding the chance of getting oral cancer significantly with 46% [OR = 0.54, 95% = 0.37-0.80] and the chance of getting Larynx Cancer significantly with 57% [OR = 0.43, 95% = 0.24-0.77] reduced.
The reduced risk was also found for eating lycopene, Alpha-carotene and beta-cryptoxanthin.
The researchers concluded that eating a lot of carotenoids the chance of getting head and neck cancer may be reduced. Possible because the overview article only case-control studies and only 1 cohort study.
Original title:
Carotenoid Intake from Natural Sources and Head and Neck Cancer: A Systematic Review and Meta-analysis of Epidemiological Studies by Leoncini E, N D, [...], Boccia S.
Link:
http://www.ncbi.nlm.nih.gov/pubmed/25873578
Additional information about El Mondo:
Find here more studies on the beschermdende effect of carotenoids against cancer.
The results found in case-control studies are less reliable than cohort studies because in case-control studies are more sensitive to errors than cohort studies. In other words, the (lowering or increasing) effect found in case-control studies should always be confirmed in cohort studies before a comment can be made.