Voedingsadvies El MondoResearch Question:
Eating vitamin C lowers the chances of getting prostate cancer?
Study Design:
This overview article contained 18 studies (6 cohort and case-control studies 12) with a total of 103658 participants.
Results and conclusions:
The researchers found that eating a lot of vitamin C, the chance of getting prostate cancer significantly with 11% [RR = 0.89, 95% CI = 0.83-0.94, p = 0.000, I2 = 39.4%, p = 0.045] reduced.
The researchers found in cohort studies that eating a lot of vitamin C, the chance of getting prostate cancer significantly with 8% [RR = 0.92, 95% CI = 0.86-0.99, p = 0.215] reduced.
The researchers found in case-control studies that eating a lot of vitamin C, the chance of getting prostate cancer significantly with 20% [RR = 0.80, 95% CI = 0.71-0.89, p = 0.000] reduced.
The researchers found in cohort studies that eating 150 mg vitamin C per day, the chance of getting prostate cancer significantly with 5% [RR = 0.95, 95% CI = 0.90-0.99, p = 0.039] reduced.
The researchers found in case-control studies that eating 150 mg vitamin C per day, the chance of getting prostate cancer significantly with 21% [RR = 0.79, 95% CI = 0.69-0.91, p = 0.001] reduced.
The researchers concluded that eating 150 mg of vitamin C per day, reduced the chance of getting prostate cancer.
Original title:
Association between Dietary Vitamin C Intake and Risk of Prostate Cancer: A Meta-analysis Involving 103,658 Subjects by Bai XY, Qu X, [...], Wu H.
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532989/
Additional information about El Mondo:
Read here more studies on vitamin C and prostate cancer.
The results found in case-control studies are less reliable than cohort studies because in case-control studies are more sensitive to errors than cohort studies. In other words, the (lowering or increasing) effect found in case-control studies should always be confirmed in cohort studies.