Voedingsadvies El MondoResearch Question:
Cholesterol levels is inconsistent associated with the risk of getting a hemorrhagic stroke. It was therefore carried out this review article.
Is there a relationship between high cholesterol and getting a hemorrhagic stroke?
Study Design:
This overview article contained 23 prospective cohort studies with 1430141 participants whose 7960 people with hemorrhagic stroke (cerebral hemorrhage).
The random effects model was used.
Results and conclusions:
The researchers found that a high total cholesterol levels compared with a low cholesterol content, the chances of getting a stroke significantly with 31% [95% CI = 0.59-0.81] reduced. Significant is, there is a link at a 95% reliability.
The researchers found that a high HDL-cholesterol levels compared with low HDL cholesterol levels, the chance of getting a stroke not significant with 2% [95% CI = 0.80-1.19] reduced.
Not significant is, there is no link to a 95% reliability.
The researchers found that a high LDL-cholesterol levels compared with low LDL cholesterol levels, the chance of getting a stroke significantly with 38% [95% CI = 0.41-0.92] reduced.
The researchers found that every increase in the total cholesterol levels with 1 mmol/L the chance of getting a stroke significantly with 15% [95% CI = 0.80-0.91] reduced.
The researchers found that any increase in the HDL-cholesterol levels with 1 mmol/L the chance of getting a brain hemorrhage are not significantly by 11% [95% CI = 0.99-1.25] increased.
The researchers found that every increase in LDL-cholesterol levels with 1 mmol/L the chance of getting a stroke not significant with 10% [95% CI = 0.77-1.05] reduced.
The researchers found that a high HDL-cholesterol levels compared with low HDL cholesterol levels, the chances of getting an intracerebral hemorrhage significantly with 17% [95% CI = 1.02-1.35] increased.
The researchers concluded that both a high total and LDL-cholesterol levels the chance of getting a brain hemorrhage while a high HDL cholesterol reduced the chances of getting an intracerebral hemorrhage increased.
Original title:
Cholesterol Levels and Risk of Hemorrhagic Stroke A Systematic Review and Meta-Analysis by Wang X, Dong Y, [...], Love L.
Link:
http://stroke.ahajournals.org/content/early/2013/05/23/STROKEAHA.113.001326.abstract
Additional information about El Mondo:
Read more about studies on cholesterol.