Voedingsadvies El MondoResearch Question:
Lowers eating vegetables, fruit or carotenoids the chance of getting kidney cancer?
Study Design:
This overview article contained 13 prospective cohort studies with a follow-up duration of 7-20 years, 1478 niercelkankergevallen (709 women and 769 men) under 774952 participants.
Validated were used FAHIM and random effects model. There was no question of heterogeneity between studies (p = 0.86).
Results and conclusions:
The researchers found that eating less than 600 grams fruit and vegetables compared with less than 200 grams per day, the risk of renal cell cancer significantly with 32% [95% CI = 0.54-0.87, P for trend = 0.001] reduced. Significant is, there is a link at a 95% reliability.
The researchers found that eating at least 400 grams of fruit compared to less than 100 grams per day, the risk of renal cell cancer significantly with 21% [95% CI = 0.63-0.99, P for trend = 0.03] reduced. Significant is, there is a link at a 95% reliability.
The researchers found that eating at least 400 g of vegetables compared to less than 100 grams per day, the risk of renal cell cancer not significant with 28% [95% CI = 0.48-1.08, P for trend = 0.07] reduced. Not significant is, there is no link to a 95% reliability.
The researchers found that every increase of 78 g broccoli a day, the risk of renal cell cancer significantly with 40% [95% CI = 0.41-0.89] reduced.
The researchers found that every increase of 57 g root per day, the risk of renal cell cancer significantly with 18% [95% CI = 0.68-0.99] reduced.
The researchers found that eating a lot of Alpha-carotene (highest compared to lowest quintile), the chance of getting renal cell not significantly with 13% [95% CI = 0.73-1.03] reduced.
The researchers found that eating a lot of beta carotene (highest compared to lowest quintile), the chance of getting renal cell cancer significantly with 18% [95% CI = 0.69-0.98] reduced.
The researchers found that eating a lot of beta-cryptoxanthin (highest compared to lowest quintile), the chance of getting renal cell not significantly by 14% [95% CI = 0.73-1.01] reduced.
The researchers found that eating lots of lutein/zeaxanthin (highest compared to lowest quintile), the chance of getting renal cell not significant with 18% [95% CI = 0.64-1.06] reduced.
The researchers found that eating lots of lycopene (highest compared to lowest quintile), the chance of getting renal cell not significantly with 13% [95% CI = 0.95-1.34] increased.
The researchers concluded that eating fruits and vegetables (minimum 600 grams fruit only, 78 grams together, 400 grams of broccoli or 57 gram roots per day) but also beta-carotene reduced the chance of getting renal cell cancer.
Original title:
Intakes or Fruit, Vegetables, and Carotenoids and Renal Cell Cancer Risk: A Pooled Analysis of 13 Prospective Studies by Lee you, Männistö S, [...], Smith-Warner SA.
Link:
http://cebp.aacrjournals.org/content/18/6/1730.short
Additional information about El Mondo:
90%-95% of the kidney cancer cases is renal cell cancer. Obsolete names for the same disease are: adenocarcinoma of the kidney, adenocarcinoma renis or Grawitz tumor. In the other cases (5 to 10%) it is referred to as cancer of the lining of the renal pelvis, which grows in the kidney tissue.
Renal cell cancer can be hereditary, but also risk factors such as smoking and factors determined by environmental, living and working environment increase the risk of renal cell cancer.
Renal cell cancer comes one and a half to two times more common in men than in women and develops higher age (65-75 years).
Read more about carotenoids.