Soja-isoflavonensupplementen verlagen de frequentie en de ernst van opvliegers

Research Question:
Can soy reduce isoflavonensupplementen hot flashes in menopausal women?

Study Design:
This overview article contained 19 Rcts.

Results and conclusions:
The meta-analysis showed that taking soy isoflavones (average 54 mg per day for 6 weeks to 12 months) significantly reduced the number of hot flashes with 20.6% (95% CI = − − 12.86 to 28.38; p 0.00001) compared to the placebo (placebo).

The meta-analysis also showed that taking soy isoflavones (average 54 mg per day for 6 weeks to 12 months) the severity of hot flashes reduced significantly with 26.2% (95% CI = − − 42.23 to 10.15, p = 0.001) relative to the placebo.

Isoflavonensupplementen that contain more than 18.8 mg genistein, were more than twice as powerful in reducing the number of hot flashes than isoflavonensupplementen with less than 18.8 mg genistein.

The researchers concluded that soy-isoflavonensupplementen (average 54 mg per day for 6 weeks to 12 months) the frequency and severity of hot flashes in women going through the menopause reduced.

Original title:
Extracted or synthesized soybean isoflavones reduce menopausal hot flash frequency and severity: systematic review and meta-analysis of randomized controlled trials by Taku K, Melby MK, [...], Messina M.

Link:
http://journals.lww.com/menopausejournal/Abstract/2012/07000/Extracted_or_synthesized_soybean_isoflavones.11.aspx

Additional information about El Mondo:
The 3 main isoflavones in soybean are genistein daidzein, and glycitein. These 3 forms are the active forms in the human body. Genistein is the most active of the three.

Products

Total isoflavones (mg)

Daidzein (mg)

Genistein (mg)

Soy beans (100 g)

128.34

46.46

73.76

Natto (100 grams)

58.93

21.85

29.04

Fried tofu (100 grams)

48.35

17.83

28

Tempeh (100 grams)

43.52

17.59

24.85

Soft tofu (100 grams)

29.24

8.59

20.6

Two good ways to hot flashes and night sweats during menopause, to reduce his weight loss and following a low-fat diet. A low-fat diet consists of products that contains 20-30% fat, And of which, a maximum of 7% saturated fat.