Voedingsadvies El MondoResearch Question:
Lowering eating fish and swallowing fish oil supplements the chance of getting heart disease?
Study Design:
This overview article contained 26 prospective cohort studies and 12 Rcts. This 38 studies gave participants 800000 together, spread over 15 countries. There was limited evidence of publication bias and heterogeneity between the studies or within the subgroups.
Results and conclusions:
The meta-analysis of cohort studies showed that people who ate fish 2-4 servings per week, significant 6% less likely walked on getting heart disease than people who ate fish 1 serving or less per week. The combined relative risk was 0.94 [95% CI = 0.90-0.98]. Significant is, it can be said with 95% reliability that the decline of 6% was really due to eating fish.
The meta-analysis of cohort studies showed that people who ate 5 or more servings of fish per week, significant 12% less chance ran on getting heart disease than people who ate 1 serving of fish per week. The combined relative risk was 0.88 [95% CI = 0.81-0.96].
The meta-analysis of Rcts with primary prevention heart disease as outcome showed that swallowing fish oil supplements the chance of getting heart disease non-significant with 2% [95% CI = 0.89-1.08] reduced. Not significant is, it cannot be said with 95% reliability that the decline of 2% was due to really swallowing fish oil supplements.
The meta-analysis of Rcts with secondary prevention of heart disease as outcome showed that swallowing fish oil supplements the chance of getting heart disease non-significant 17% [95% CI = 0.99-1.38] increased. Not significant is, it cannot be said with 95% reliability that the rise was due to the 17% really swallowing fish oil supplements.
The researchers concluded that eating fish the chance of getting heart disease reduced. However, swallowing fish oil supplements reduced the chance of getting heart disease
Original title:
Association between fish consumption, long chain omega 3 fatty acids, and risk or cerebrovascular disease: systematic review and meta-analysis by Chowdhury R, Stevens S, [...], Franco OH.
Link:
http://www.bmj.com/highwire/filestream/611772/field_highwire_article_pdf/0/bmj.e6698
Additional information about El Mondo:
For years is the reduced risk of heart disease attributed to the omega-3 fatty acids EPA and DHA (the two main visvetzuren in fish oil supplements). But there is more and more scientific evidence that swallowing of EPA and DHA chances of getting heart disease not lowers. In other words, scientists are no longer convinced of the causal link between EPA and DHA and the reduced risk of cardiovascular disease.
While science is about to move away from the causal link between the omega-3 fatty acids and heart disease, the food industry about to more omega-3 fatty acids to add to its products with the claim that omega-3 fatty acids good for heart and blood vessels.
1 serving of fish is 100-150 grams.