Voedingsadvies El MondoResearch Question:
Eating alpha-linolenic acid reduces the chance of getting heart disease?
Study Design:
This overview article contained 27 studies (No RCTs) with 251049 participants, 15327 which patients with heart disease.
Results and conclusions:
The researchers found that the intake of alpha-linolenic acid the chance of getting heart disease significantly with 14% [95% CI = 0.77-0.97, I2 = 71.3%] reduced.
The researchers found that the intake of alpha-linolenic acid via diet, chances of getting heart disease significantly with 10% [95% CI = 0.99-0.99, I2 = 49.0%] reduced.
The researchers found that the intake of alpha-linolenic acid measured by biomarkers, the chance of getting heart disease non-significant with 20% [95% CI = 0.63-1.03, I2 = 79,8%] reduced.
The researchers concluded that eating a lot of alpha-linolenic acid (measured through feeding) the possible reduced risk of cardiovascular disease. Possible because of the high unexplained heterogeneity.
Original title:
α-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis by Pan A, Chen M, [...], Hu FB.
Link:
http://www.ncbi.nlm.nih.gov/pubmed/23076616
Additional information about El Mondo:
Read more about alpha-linolenic acid.
Read more about overview article, I2 and 95% CI.