Objectives:
Have flaxseed supplementation positive effects on body composition?

Study design:
This review article included a total of 45 RCTs.

Results and conclusions:
The investigators found a significant reduction in body weight [WMD = -0.99 kg, 95% CI = -1.67 to -0.31, p = 0.004], BMI [WMD = -0.30 kg m², 95% CI = -0.53 to -0.08, p = 0.008] and waist circumference [WMD = -0.80 cm, 95% CI = -1.40 to -0.20, p = 0.008] following flaxseed supplementation.

Scientific studies (review articles) on the relationship between nuts&seeds and disease prevention:
One swallow does not make a summer. A famous Dutch saying that could not be any more obvious. Just because one single scientific study about a certain topic makes certain claims, it does not necessarily mean it is true. On the other hand, a review article (a collection of scientific studies on a certain topic) of randomized, placebo-controlled double blind clinical trials (RCTs) will answer the following question:

Objectives:
Iron deficiency is a prevalent nutritional disease and fatigue is a common complaint in the general and patient population, however, the association between iron deficiency without anaemia (IDNA) and fatigue is unclear. Therefore, this review article (meta-analysis) has been conducted.

Does improving iron status decrease fatigue in patients with iron deficiency without anaemia?

Study design:
This review article included a total of 6 RCTs and 6 cross-sectional studies.

Objectives:
Studies implicate choline and betaine metabolite trimethylamine N-oxide (TMAO) in cardiovascular disease (CVD). Therefore, this review article (meta-analysis) has been conducted.

Is there an association between choline and betaine dietary intake and cardiovascular disease?

Scientific studies on the relationship between choline and disease prevention:
One swallow does not make a summer. A famous Dutch saying that could not be any more obvious. Just because one single scientific study about a certain topic makes certain claims, it does not necessarily mean it is true. On the other hand, a review article (a collection of scientific studies on a certain topic) of randomized, placebo-controlled double blind clinical trials (RCTs) will answer the following question:

Objectives:
The clinical benefits of perioperative antioxidant vitamin therapy in cardiac patients remain controversial. Therefore, this review article (meta-analysis) has been conducted.

Do patients undergoing cardiac surgery benefit from perioperative antioxidant vitamin therapy?

Objectives:
Previous studies have demonstrated that asthma might be associated with an increase in cardiovascular disease (CVD) and death. However, this relationship differs by gender. Therefore, this review article (meta-analysis) has been conducted.

Is asthma associate with an increase risk in cardiovascular disease and death among men and women?

Study design:

Objectives:
Although several epidemiological studies have investigated the association between dietary calcium intake and the risk of esophageal cancer, the results are inconsistent. Therefore, this review article (meta-analysis) has been conducted.

Does dietary calcium intake reduce risk of esophageal cancer?

Study design:
This review article included 3 cohort studies and 14 case-control studies, including 3,396 cases (subjects with esophageal cancer) and 346,815 controls (subjects without esophageal cancer).

Objectives:
Have flaxseed supplementation positive effects on body composition?

Study design:
This review article included a total of 45 RCTs.

Results and conclusions:
The investigators found a significant reduction in body weight [WMD = -0.99 kg, 95% CI = -1.67 to -0.31, p = 0.004], BMI [WMD = -0.30 kg m², 95% CI = -0.53 to -0.08, p = 0.008] and waist circumference [WMD = -0.80 cm, 95% CI = -1.40 to -0.20, p = 0.008] following flaxseed supplementation.

Objectives:
The associations between n-3 polyunsaturated fatty acids (PUFAs) and metabolic syndrome (MetS) risk have demonstrated inconsistent results. Therefore, this review article (meta-analysis) has been conducted.