Objectives:
Does hydroxychloroquine supplementation show beneficial effects in patients affected by mild to moderate COVID-19 disease?

Objectives:
Prevention of mother-to-child transmission (MTCT) of hepatitis B virus (HBV) involves neonatal immunoprophylaxis, with a birth dose of hepatitis B vaccine and immune globulin, and provision of peripartum antiviral prophylaxis in highly viraemic women. However, access to assays to quantify HBV DNA levels remains inadequate in resource-poor settings. Therefore, this review article has been conducted.

Objectives:
Obesity accompanied by excess ectopic fat storage has been postulated as a risk factor for severe disease in people with SARS-CoV-2 (COVID-19) through the stimulation of inflammation, functional immunologic deficit and a pro-thrombotic disseminated intravascular coagulation with associated high rates of venous thromboembolism. Therefore, this review article has been conducted.

Is an increased BMI a risk factor for severe disease and death with COVID‐19?

Objectives:
Could chest CT manifestations in children with COVID-19 be used for early identification and prompt intervention in the pediatric population?  

Study design:
This review article included 29 articles with 1,026 COVID-19 pediatric patients (0-18 years).

Results and conclusions:   
The investigators found over a third of pediatric patients with COVID-19 [35.7%, 95% CI = 27.5% to 44%] had normal chest CT scans and only 27.7% [95% CI = 19.9% to 35.6%] had bilateral lesions.

Objectives:
Observational studies regarding the putative associations between dietary intake of homocysteine metabolism-related B-vitamins (vitamin B6, folate and vitamin B12) and stroke risk have yielded inconsistent results. Therefore, this review article has been conducted.

Does dietary intake of vitamin B6, folate or vitamin B12 reduce stroke risk?

Study design:
This review article included 1 nested case-control study and 11 prospective cohort studies comprising 389,938 participants and 10,749 cases (persons with stroke).

Objectives:
The association between acute kidney injury (AKI) and outcome of coronavirus disease 2019 (COVID-19) has not yet been conclusively established. Therefore, this review article has been conducted.

Is acute kidney injury associated with worse prognosis in COVID-19 patients?  

Objectives:
By sustaining transmission or causing malaria outbreaks, imported malaria undermines malaria elimination efforts. Few studies have examined the impact of travel on malaria epidemiology. Therefore, this review article has been conducted.

Is travel an important risk factor for malaria infection in sub-Saharan Africa?

Study design:
This review article included 22 studies, conducted in sub-Saharan Africa.

There was substantial heterogeneity in the magnitude of association across the studies.

Objectives:
There remains controversy over the usage of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) in patients with coronavirus disease 2019 (COVID-19) given their interaction with the angiotensin converting enzyme-2 (ACE-2) receptor mechanism. Therefore, this review article has been conducted.

What is the impact of ACEI/ARB on COVID-19 associated disease severity and mortality?  

Study design:
This review article included 21 studies.

Objectives:
At present, existing evidence about the association between SARS-CoV-2 (COVID-19) infection and ABO blood group polymorphism is preliminary and controversial. Therefore, this review article has been conducted.

Is ABO blood group associated with SARS-CoV-2 (COVID-19) risk?  

Study design:
This review article included 7 studies with a total of 13 subgroups of populations (7,503 COVID-19 positive cases and 2,962,160 controls).

Objectives:
Does hip fracture increase risk of mortality among COVID-19 patients?

Study design:
This review article included 6 studies with a total of 984 participants.
Regression-based Harbord's test showed no indication of small-study effects [p = 0.06].  

Results and conclusions:   
The investigators found pooled prevalence of COVID-19 was 9% [95% CI = 7% to 11%].