Objectives:
Does niacin (vitamin B3) supplementation improve lipid profiles and glycemic control in patients with type 2 diabetes mellitus?

Study design:
This review article included 8 RCTs comprised a total of 2,110 patients with type 2 diabetes mellitus.
Studies published ranged from 1990 to 2016 and 15 to 1,053 patients were included in each individual trial.

The follow-up duration ranged from 8.0 weeks to 12.0 months.

Objetivos:
¿Mejora la suplementación con niacina (vitamina B3) los perfiles lipídicos y el control glucémico en los pacientes con diabetes mellitus tipo 2?

Diseño del estudio:
Este artículo de revisión incluyó 8 ensayos doble-ciegos, aleatorizados, placebo controlados con un total de 2,110 pacientes con diabetes mellitus tipo 2.

Los estudios publicados variaron de 1990 a 2016 y se incluyeron de 15 a 1,053 pacientes en cada ensayo individual.

La duración del seguimiento osciló entre 8 semanas y 12 meses.

Objectives:
Does tocilizumab decrease mortality risk among COVID-19 patients?

Objectives:
Coronavirus disease 2019 (COVID-19) has become global pandemic and resulted in considerable morbidity and mortality since December 2019. Information on the incidence of myocardial injury remains scarce. Therefore, this review article has been conducted.

Does myocardial injury increase severe COVID-19 infection?

Objectives:
Hookworm is an intestinal parasite that infects nearly 230 million people, with another 5.1 billion at risk, especially in poverty-stricken tropical and subtropical regions. Pregnancy is an especially vulnerable time for hookworm infection because of its effect on both maternal and subsequently fetal health. Therefore, this review article has been conducted.

Objectives:
The number of cancer survivors is growing rapidly worldwide, especially long-term survivors. Although a healthy diet with a high vegetable and fruit consumption is a key factor in primary cancer prevention, there is a lack of specific dietary recommendations for cancer survivors, except in the case of breast cancer [World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) report]. Therefore, this review article (meta-analysis) has been conducted.

Objectives:
The COVID-19 causing coronavirus is an enveloped RNA virus that utilizes an enzyme RNA dependent RNA polymerase for its replication. Favipiravir (FVP) triphosphate, a purine nucleoside analog, inhibits that enzyme. Therefore, this review article has been conducted.

Objectives:
An outbreak of Corona Virus Disease 2019 (COVID-19) has spread rapidly reaching over 3 million of confirmed cases worldwide. The association of respiratory diseases and smoking, both highly prevalent globally, with COVID-19 severity has not been elucidated. Therefore, this review article has been conducted.

Objectives:
Do elevated D-dimer levels increase risk of severe and mortality among patients with COVID-19 infection?

Study design:
This review article included 18 studies (16 retrospective and 2 prospective) with a total of 3,682 COVID-19 patients.

Results and conclusions:   
The investigators found pooled weighted mean difference (WMD) demonstrated significantly elevated D-dimer levels in patients who died versus those who survived [WMD = 6.13 mg/L, 95% CI = 4.16 to 8.11, p 0.001].

Objectives:
What is the incubation period of COVID-19?

Study design:
This review article included 7 studies (n = 792).
The heterogeneity [I2 = 83.0%, p 0.001] was significantly decreased after including the study quality and the statistical model used as moderator variables [I2 = 15%].

Results and conclusions: