Convalescent plasma treatment reduces mortality rate among COVID-19 patients

Objectives:
Does convalescent plasma treatment reduce mortality rate among COVID-19 patients?

Study design:
This review article included 38 studies with a total of 27,706 COVID-patients, of which 3,262 (2,127 in convalescent plasma-treated (CPT) group and 1,135 in the non-convalescent plasma/control group) patients died.

Overall, risk-of-bias assessment showed that the included studies had low to medium risk of bias.

Results and conclusions:   

A loading dose of tafenoquine alone is effective in preventing malaria in short-term travellers

Objectives:
Chemoprophylaxis with weekly doses of tafenoquine (200 mg/day for 3 days before departure [loading dose], 200 mg/week during travel and one-week post-travel [maintenance doses]) is effective in preventing malaria. Effectiveness of malaria chemoprophylaxis drugs in travellers is often compromised by poor compliance. Shorter schedules that can be completed before travel, allowing “drug-free holidays”, could increase compliance and thus reduce travel-related malaria. Therefore, this review article (meta-analysis) has been conducted.

1.5 g/day garlic supplementation reduces adiponectin level among participants ˂30 years

Objectives:
Does garlic supplementation reduce adiponectin and leptin serum levels?

Study design:
This review article included 5 RCTs.

Results and conclusions:
The investigators found that garlic supplementation did not significantly affect adiponectin [Hedges's = 0.20, 95% CI = -0.06 to 0.47, p = 0.12] and leptin [Hedges's = 0.08, 95% CI = -0.26 to 0.41, p = 0.65] concentrations in comparison with placebo.

Tart cherry supplementation improves recovery from strenuous exercise

Objectives:
Does tart cherry (TC) supplementation improve recovery following strenuous exercise?

Study design:
This review article included 14 studies.

Results and conclusions:
The investigators found tart cherry supplementation had a small significant beneficial effect in reducing muscle soreness [effect size (ES) = -0.44, 95% CI = -0.87 to -0.02].

High-dose methylprednisolone probably decreases mortality from COVID-19

Objectives:
The questions remained if mortality benefits with dexamethasone seen in patients with coronavirus disease 2019 (COVID-19) also extend to other systemic corticosteroids such as methylprednisolone. Therefore, this review article has been conducted.

Does methylprednisolone decrease mortality from COVID-19?

Study design:
This review article included 5 RCTs.  

No association between potato consumption and cancers

Objectives:
The etiology of cancer type may vary significantly due to anatomy, embryology and physiology of the cancer site. Although the association between potato consumption and colorectal cancer (CRC) was summarized in a 2018 meta-analysis of 5 cohort studies, however, no meta-analysis has evaluated potato consumption in relation to multiple cancer sites in adults. Therefore, this review article has been conducted.

Anti-cancer therapy have no adverse effects on severity and mortality in cancer patients with COVID-19

Objectives:
Coronavirus disease-2019 (COVID-19) poses a serious health threat to people around the world, particularly in patients with cancer. Whether or not cancer patients infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) receive anti-cancer therapy is associated with a poor prognosis is unclear. Therefore, this review article has been conducted.